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1

Live single-cell video-mass spectrometry for cellular and subcellular molecular detection and cell classification

Hajime Mizuno, Naohiro Tsuyama, Takanori Harada, Tsutomu Masujima

Journal:

Journal of Mass Spectrometry

Year:

2008

Language:

english

File:

PDF, 522 KB

english, 2008

2

Direct metabolomics for plant cells by live single-cell mass spectrometry

Fujii, Takashi, Matsuda, Shuichi, Tejedor, Mónica Lorenzo, Esaki, Tsuyoshi, Sakane, Iwao, Mizuno, Hajime, Tsuyama, Naohiro, Masujima, Tsutomu

Journal:

Nature Protocols

Year:

2015

Language:

english

File:

PDF, 2.80 MB

english, 2015

3

The great importance of normalization of LC-MS data for highly-accurate non-targeted metabolomics

Mizuno, Hajime, Ueda, Kazuki, Kobayashi, Yuta, Tsuyama, Naohiro, Todoroki, Kenichiro, Min, Jun Zhe, Toyo'oka, Toshimasa

Journal:

Biomedical Chromatography

Year:

2016

Language:

english

File:

PDF, 523 KB

english, 2016

4

Live Single-cell Mass Spectrometry for Organelle Metabolomics

MIZUNO, Hajime, TSUYAMA, Naohiro, MASUJIMA, Tsutomu

Journal:

Year:

2014

File:

PDF, 1.35 MB

2014

5

Dose–response curves for analyzing of dicentric chromosomes and chromosome translocations following doses of 1000 mGy or less, based on irradiated peripheral blood samples from five healthy individuals

Abe, Yu, Yoshida, Mitsuaki A, Fujioka, Kurumi, Kurosu, Yumiko, Ujiie, Risa, Yanagi, Aki, Tsuyama, Naohiro, Miura, Tomisato, Inaba, Toshiya, Kamiya, Kenji, Sakai, Akira

Journal:

Journal of Radiation Research

Year:

2018

Language:

english

File:

PDF, 523 KB

english, 2018

6

Resin-packed nanoelectrospray in combination with video and mass spectrometry for the direct and real-time molecular analysis of mast cells

Anusak Sirikatitham, Takahiro Yamamoto, Masakazu Shimizu, Tomomi Hasegawa, Naohiro Tsuyama, Tsutomu Masujima

Journal:

Rapid Communications in Mass Spectrometry

Year:

2007

Language:

english

File:

PDF, 267 KB

english, 2007

7

Interleukin-6—Induced Proliferation of Human Myeloma Cells Associated with CD45 Molecules

Hideaki Ishikawa, Naohiro Tsuyama, Michio M. Kawano

Journal:

International Journal of Hematology

Year:

2003

Language:

english

File:

PDF, 254 KB

english, 2003

8

Growth mechanism of human myeloma cells by interleukin-6

Michio M. Kawano, Hideaki Ishikawa, Naohiro Tsuyama, Saeid Abroun, Shangqin Liu, Fu-Jun Li, Ken-ichiro Otsuyama, Xu Zheng

Journal:

International Journal of Hematology

Year:

2002

Language:

english

File:

PDF, 750 KB

english, 2002

9

Genetic Alterations in Thyroid Tumor Progression: Association with p53 Gene Mutations

Takashi Ito, Toshio Seyama, Terumi Mizuno, Naohiro Tsuyama, Yuzo Hayashi, Kiyohiko Dohi, Nori Nakamura, Mitoshi Akiyama

Journal:

Year:

1993

File:

PDF, 587 KB

1993

10

Differential regulation of human RecQ family helicases in cell transformation and cell cycle

Kawabe, Tamae, Tsuyama, Naohiro, Kitao, Saori, Nishikawa, Kaori, Shimamoto, Akira, Shiratori, Miwa, Matsumoto, Takehisa, Anno, Kumiko, Sato, Tatsuhiro, Mitsui, Youji

Journal:

Year:

2000

Language:

english

File:

PDF, 279 KB

english, 2000

11

Accelerated proliferation of myeloma cells by interleukin-6 cooperating with fibroblast growth factor receptor 3-mediated signals

Ishikawa, Hideaki, Tsuyama, Naohiro, Liu, Shangqin, Abroun, Saeid, Li, Fu-Jun, Otsuyama, Ken-ichiro, Zheng, Xu, Ma, Zi, Maki, Yasuko, Iqbal, Mohd S

Journal:

Year:

2005

Language:

english

File:

PDF, 250 KB

english, 2005

12

Increased susceptibility to apoptosis in CD45+ myeloma cells accompanied by the increased expression of VDAC1

Liu, Shangqin, Ishikawa, Hideaki, Tsuyama, Naohiro, Li, Fu-Jun, Abroun, Saeid, Otsuyama, Ken-ichiro, Zheng, Xu, Ma, Zi, Maki, Yasuko, Iqbal, Mohd S, Obata, Masanori, Kawano, Michio M

Journal:

Year:

2005

Language:

english

File:

PDF, 312 KB

english, 2005

13

Elevated in vivo frequencies of mutant T cells with altered functional expression of the T-cell receptor or hypoxanthine phosphoribosyltransferase genes in p53-deficient mice

Takako Suzuki, Yoichiro Kusunoki, Naohiro Tsuyama, Hisashi Ohnishi, Toshio Seyama, Seishi Kyoizumi

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2001

Language:

english

File:

PDF, 70 KB

english, 2001

14

Telomerase activity in hybrids between telomerase-negative and telomerase-positive immortal human cells is repressed in the different complementation groups but not in the same complementation group of immortality

Yuriko Ishii, Naohiro Tsuyama, Shizuko Maeda, Hidetoshi Tahara, Toshinori Ide

Journal:

Mechanisms of Ageing and Development

Year:

1999

Language:

english

File:

PDF, 454 KB

english, 1999

15

AhVti1Homologue: Its Expression Depends on Population Doubling Levels in both Normal and SV40-Transformed Human Fibroblasts

Hu-Chun Li, Hidetoshi Tahara, Naohiro Tsuyama, Toshinori Ide

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 777 KB

english, 1998

16

IL-6-induced Bcl6 variant 2 supports IL-6-dependent myeloma cell proliferation and survival through STAT3

Naohiro Tsuyama, Inaho Danjoh, Ken-ichiro Otsuyama, Masanori Obata, Hidetoshi Tahara, Tsutomu Ohta, Hideaki Ishikawa

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 179 KB

english, 2005

17

A novel signaling pathway associated with Lyn, PI 3-kinase and Akt supports the proliferation of myeloma cells

Mohd S. Iqbal, Naohiro Tsuyama, Masanori Obata, Hideaki Ishikawa

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 817 KB

english, 2010

18

In Situ Molecular Analysis of Plant Tissues by Live Single-Cell Mass Spectrometry

Lorenzo Tejedor, Mónica, Mizuno, Hajime, Tsuyama, Naohiro, Harada, Takanori, Masujima, Tsutomu

Journal:

Analytical Chemistry

Year:

2012

Language:

english

File:

PDF, 474 KB

english, 2012

19

Drug metabolite heterogeneity in cultured single cells profiled by pico-trapping direct mass spectrometry

Fukano, Yasufumi, Tsuyama, Naohiro, Mizuno, Hajime, Date, Sachiko, Takano, Mikihisa, Masujima, Tsutomu

Journal:

Year:

2012

Language:

english

File:

PDF, 900 KB

english, 2012

20

CD19 Expression and Growth Inhibition of Tumours in Human Multiple Myeloma

Ishikawa, Hideaki, Tsuyama, Naohiro, Mahmoud, Maged S., Fujii, Ryuichi, Abroun, Saeid, Liu, Shangqin, Li, Fu-Jun, Kawano, Michio M.

Journal:

Leukemia and Lymphoma

Year:

2002

Language:

english

File:

PDF, 165 KB

english, 2002

21

The usefulness of severe combined immunodeficiency (SCID) mice to study human carcinogenesis

Ito, Takashi, Seyama, Toshio, Kyoizumi, Seishi, Teraoka, Seigo, Iwamoto, Keisuke S., Mizuno, Terumi, Tsuyama, Naohiro, Asahara, Toshimasa, Dohi, Kiyohiko, Akiyama, Mitoshi

Journal:

Year:

1995

Language:

english

File:

PDF, 2.08 MB

english, 1995

22

Nanokinetics of drug molecule transport into a single cell

Tamura, Atsushi, Ozawa, Koichiro, Ohya, Tatsuo, Tsuyama, Naohiro, Eyring, Edward M, Masujima, Tsutomu

Journal:

Year:

2006

Language:

english

File:

PDF, 672 KB

english, 2006

23

The “white globe appearance” (WGA): a novel marker for a correct diagnosis of early gastric cancer by magnifying endoscopy with narrow-band imaging (M-NBI)

Doyama, Hisashi, Yoshida, Naohiro, Tsuyama, Sho, Ota, Ryosuke, Takeda, Yasuhito, Nakanishi, Hiroyoshi, Tsuji, Kunihiro, Tominaga, Kei, Tsuji, Shigetsugu, Takemura, Kenichi, Yamada, Shinya, Katayanagi,

Journal:

Endoscopy International Open

Year:

2015

Language:

english

File:

PDF, 403 KB

english, 2015

24

Videovisualization of dynamic cell responses and its molecular analysis for nanomedicine

Masujima, Tsutomu, Tsuyama, Naohiro, Hasegawa, Tomomi

Journal:

Year:

2006

Language:

english

File:

PDF, 1.67 MB

english, 2006

25

Analysis of chromosome translocation frequency after a single CT scan in adults

Abe, Yu, Miura, Tomisato, Yoshida, Mitsuaki A., Ujiie, Risa, Kurosu, Yumiko, Kato, Nagisa, Katafuchi, Atsushi, Tsuyama, Naohiro, Kawamura, Fumihiko, Ohba, Takashi, Inamasu, Tomoko, Shishido, Fumio, No

Journal:

Journal of Radiation Research

Year:

2016

Language:

english

File:

PDF, 221 KB

english, 2016

26

The Regulatory Mechanism of IL-6-dependent Proliferation of Human Myeloma Cells

Abroun, Saeid, Liu, Shangqin, Tsuyama, Naohiro, Otsuyama, Ken-Ichiro, Ishikawa, Hideaki, Zheng, Xu, Obata, Masanori, taniguchi, Osamu, Kawano, Michio M., Li, Fu-Jun

Journal:

Hematology (American Society of Hematology)

Year:

2003

Language:

english

File:

PDF, 322 KB

english, 2003

27

White globe appearance is a novel specific endoscopic marker for gastric cancer: A prospective study

Yoshida, Naohiro, Doyama, Hisashi, Nakanishi, Hiroyoshi, Tsuji, Kunihiro, Tominaga, Kei, Matsunaga, Kazuhiro, Tsuji, Shigetsugu, Takemura, Kenichi, Yamada, Shinya, Tsuyama, Sho, Katayanagi, Kazuyoshi,

Journal:

Digestive Endoscopy

Year:

2016

Language:

english

File:

PDF, 325 KB

english, 2016

28

Molecular and Functional Analysis of Cellular Phenomena Using Single-Cell Mass Spectrometry

Tsuyama, Naohiro, Mizuno, Hajime, Masujima, Tsutomu

Year:

2012

Language:

english

File:

PDF, 2.82 MB

english, 2012

29

Live Single-cell Metabolomics of Tryptophan and Histidine Metabolites in a Rat Basophil Leukemia Cell

MIZUNO, Hajime, TSUYAMA, Naohiro, DATE, Sachiko, HARADA, Takanori, MASUJIMA, Tsutomu

Journal:

Analytical Sciences

Year:

2008

Language:

english

File:

PDF, 545 KB

english, 2008

30

Direct Single-Cell Molecular Analysis of Plant Tissues by Video Mass Spectrometry

LORENZO TEJEDOR, Mónica, MIZUNO, Hajime, TSUYAMA, Naohiro, HARADA, Takanori, MASUJIMA, Tsutomu

Journal:

Analytical Sciences

Year:

2009

Language:

english

File:

PDF, 1.88 MB

english, 2009

31

Live Single-Cell Molecular Analysis by Video-Mass Spectrometry

TSUYAMA, Naohiro, MIZUNO, Hajime, TOKUNAGA, Emi, MASUJIMA, Tsutomu

Journal:

Analytical Sciences

Year:

2008

Language:

english

File:

PDF, 522 KB

english, 2008

32

Mass Spectrometry for Cellular and Tissue Analyses in a Very Small Region

TSUYAMA, Naohiro, MIZUNO, Hajime, MASUJIMA, Tsutomu

Journal:

Analytical Sciences

Year:

2011

Language:

english

File:

PDF, 1.71 MB

english, 2011

33

Visualization of Radiation Dose by Bioanalytical Methods

TSUYAMA, Naohiro

Journal:

Year:

2014

File:

PDF, 1.26 MB

2014

34

Direct Drug Metabolism Monitoring in a Live Single Hepatic Cell by Video Mass Spectrometry

DATE, Sachiko, MIZUNO, Hajime, TSUYAMA, Naohiro, HARADA, Takanori, MASUJIMA, Tsutomu

Journal:

Analytical Sciences

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

35

Establishment of induced pluripotent stem cells from normal B cells and inducing AID expression in their differentiation into hematopoietic progenitor cells

Kawamura, Fumihiko, Inaki, Makoto, Katafuchi, Atsushi, Abe, Yu, Tsuyama, Naohiro, Kurosu, Yumiko, Yanagi, Aki, Higuchi, Mitsunori, Muto, Satoshi, Yamaura, Takumi, Suzuki, Hiroyuki, Noji, Hideyoshi, Su

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 3.06 MB

english, 2017

36

Academic Responses to Fukushima Disaster

Yasui, Kiyotaka, Kimura, Yuko, Kamiya, Kenji, Miyatani, Rie, Tsuyama, Naohiro, Sakai, Akira, Yoshida, Koji, Yamashita, Shunichi, Chhem, Rethy, Abdel-Wahab, May, Ohtsuru, Akira

Journal:

Asia-Pacific Journal of Public Health

Year:

2017

Language:

english

File:

PDF, 524 KB

english, 2017

37

Increase in dicentric chromosome formation after a single CT scan in adults

Abe, Yu, Miura, Tomisato, Yoshida, Mitsuaki A., Ujiie, Risa, Kurosu, Yumiko, Kato, Nagisa, Katafuchi, Atsushi, Tsuyama, Naohiro, Ohba, Takashi, Inamasu, Tomoko, Shishido, Fumio, Noji, Hideyoshi, Ogawa

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 724 KB

english, 2015

38

In Memory of Prof. Masujima: Footsteps Leading to Great Achievement in “Live Single-Cell Mass Spectrometry”

MIZUNO, Hajime, TSUYAMA, Naohiro

Journal:

Journal of the Mass Spectrometry Society of Japan

Year:

2017

File:

PDF, 2.24 MB

2017

39

Induction of t(11;14) IgH enhancer/promoter‑cyclin D1 gene translocation using CRISPR/Cas9

Tsuyama, Naohiro, Abe, Yu, Yanagi, Aki, Yanai, Yukari, Sugai, Misaki, Katafuchi, Atsushi, Kawamura, Fumihiko, Kamiya, Kenji, Sakai, Akira

Journal:

Oncology Letters

Year:

2019

Language:

english

File:

PDF, 781 KB

english, 2019

40

Investigation of the cumulative number of chromosome aberrations induced by three consecutive CT examinations in eight patients

Abe, Yu, Noji, Hideyoshi, Miura, Tomisato, Sugai, Misaki, Kurosu, Yumiko, Ujiie, Risa, Tsuyama, Naohiro, Yanagi, Aki, Yanai, Yukari, Ohba, Takashi, Ishikawa, Tetsuo, Kamiya, Kenji, Yoshida, Mitsuaki A

Journal:

Journal of Radiation Research

Year:

2019

Language:

english

File:

PDF, 637 KB

english, 2019

41

Mitogenic Signals Initiated via Interleukin-6 Receptor Complexes in Cooperation with Other Transmembrane Molecules in Myelomas

Ishikawa, Hideaki, Tsuyama, Naohiro, Obata, Masanori, M. Kawano, Michio

Journal:

Journal of Clinical and Experimental Hematopathology

Year:

2006

File:

PDF, 469 KB

2006

42

Simple, Rapid, Quantitative, and Sensitive Detection of Telomere Repeats in Cell Lysate by a Hybridization Protection Assay

Nakamura, Yasuhiro, Hirose, Minoru, Matsuo, Hajime, Tsuyama, Naohiro, Kamisango, Keiichi, Ide, Toshinori

Journal:

Clinical Chemistry

Year:

1999

File:

PDF, 347 KB

1999

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